AstraZeneca's Covid vaccine suffers a setback in nasal spray trial

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LONDON, Oct 11 ― Attempts by Oxford University researchers and AstraZeneca Plc to create a nasal-spray version of their jointly developed Covid-19 shot suffered a setback today as initial testing on humans did not yield the desired protection.An antibody response in the respiratory mucous membranes was seen in only a minority of participants in the trial, which was in the first of usually three phases of clinical testing, the University of Oxford said in a statement today.Also, the immune response measured in the blood was weaker than that from a shot-in-the-arm vaccination.Researchers across the world have placed high hopes on nasal spray vaccines against the coronavirus because the method is believed to potentially prevent infection and not just disease as it may prompt an immune response directly in the airways, where the virus enters the body.In addition, the method would …